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Medical Effects of UBI

History & Efficacy of UBI Therapy

In the 1940s, a multitude of articles appeared in the American literature detailing a novel treatment for infection. This treatment had a cure rate of 98 to 100% in early and moderately advanced infections, and approximately 50% in terminally moribund patients. Healing was not limited to just bacterial infections, but also viral (acute polio), wounds, asthma, and arthritis. Recent German literature has demonstrated profound improvements in a number of biochemical and hematological markers. There has never been reported any toxicity, side effects or injury except for occasional Herxheimer type reactions. “As infections are failing to improve with the use of chemical treatment, this safe and effective treatment should be revisited”. (Int. Journal of Biosocial Medical Research., 1996; 14{2}: {115-132})

Ultraviolet (UV) light has been known for decades to have a sterilizing effect and has been used in many different industries for such a purpose. Almost all bacteria may be killed or attenuated by ultraviolet rays, and as such, acts as an auto-vaccine. But there is considerable variation in the rapidity of their destruction. Those which live in the body are most easily affected, while those in nature adapt to the action of sunlight and become relatively resistant to irradiation. UV-sensitive bacteria have not been shown to become resistant and toxins have been found to be very unstable in the presence of UV irradiation (Diphtheria, tetanus, and snake venom are inactivated by ultraviolet rays).

Technique

The procedure for administering the UBI treatment is very simple.

First, a doctor must be well trained in UBI by doctors who have the experience and medical expertise in using UBI technology. 1.5 cc. of blood per pound of body weight (never to exceed 250 cc.) or 5% of blood volume is withdrawn by venipuncture into a transfusion flask fixed with a small amount of Heparin (used to prevent coagulation of blood). The blood then flows from the flask fixed with a filter and in tubing through a synchronized pump which propels it at an automatically controlled rate. The blood continues through an irradiation chamber where it is exposed to a controlled amount of ultraviolet energy in the accepted therapeutic band. The irradiated blood then returns to the patient through the same needle used for withdrawal of the blood. Average treatment time is only 30 minutes from setup to cleanup. The above technique was developed by Dr. Emmett Knott in 1924.

German Findings

Recent German research reports significant improvement in vascular conditions when using ultraviolet blood irradiation, including peripheral arterial disease and Ravnaud's disease. One study demonstrated a 124% increase in painless walking for patients with Stage Ilb occlusive disease (Fontaine), as compared to 48% improvement with pentoxifylline. [29] UV blood irradiation was found to improve claudication distances by 90% after a series of ten treatments.[30] The authors also reported an 8% drop in plasma viscosity with the treated group, compared to no change with Pentoxifylline.

Significant changes and improvements in physiologic, biochemical, and blood Theological properties have been observed. A summary of these effects, based on the works of Frick [31] appear in Table 5 [32] This article expanded on indications to all circulatory diseases, including post-apoplexy, diabetes, venous ulcers, and migraines.

Frick reported an increase in prostacyclin and a reduction in arteriosclerotic plaque. The biochemical effects are generated by the activation of molecular oxygen to singlet oxygen by UV energy. This active species initiates a cascade of molecular reactions, resulting in the observed effects. Ultimately, this controlled oxidation process leads to a rise in the principle antioxidant enzyme systems of the body - catalase, superoxide dismutase, and glutathione peroxidase. Contraindications included porphyria, photosensitivity, coagulopathy (hemophilia), hyperthyroidism, and fever of unknown origin, but not pregnancy.

Discussion

In the 1800s, arguments raged between Pasteur and his rival, Bechamp, over the true cause of infectious disease. Pasteur claimed the cause was the organism alone, while Bechamp claimed the disease rose from organisms already within the body, which had pleomorphic capability (the ability to change). It is rumored that Pasteur, on his deathbed, admitted that Bechamp was correct. Forgotten in the debate was Bernard who argued it was the terrain or fertility of the body which permitted disease or allowed bacterial infection to take root. Perhaps UV blood irradiation can be explained best in the general effect of the treatment on the physiology and terrain of the body. For example, it is known that the phagocytic respiratory burst, in response to infection, consumes up to 100 times the oxygen that white cells require in the resting state. The improvement in oxidation, rise in red blood cells, and increase in red cell 2,3 DGP[33] may provide a significant boost to the body.

Findings of German Research

エッチBiophysical and Chemical Effects

• 優良エッチ Improvement of the electrophoretic movability of the red blood cells
• Elevation of the electrical charge on the red blood cell
• Lowering of the surface tension of the blood
• Origin of free radicals
• Elevation of the chemical illuminescence of blood

エッチHematologic Changes

• 優良エッチ Increase in erythrocytes
• Increase in hemoglobin
• Increase in basophilic granulocytes
• Lowering of thrombocytes
• Increase in white blood cells
• Increase in lymphocytes

エッチHemostatic Changes

• 優良エッチ Lowering of fibrin
• Normalization of fibrinolysis
• Trend towards normalization of fibrin-split products
• Lowering of platelet aggregation

エッチBlood Parameter Changes

• Lowering of full-blood viscosity
• Lowering of plasma viscosity
• Reduction of elevated red blood cell aggregation tendencies

エッチMetabolic Changes - Improvement in Oxygen Utilization

• Increase in arterial pO2
• Increase in venous pO2
• Increase in arterial venous oxygen difference (increased oxygen release)
• Increase in peroxide count
• Fall in oxidation state of blood (increase in reduction state)
• Increase in acid-buffering capacity and rise in blood pH
• Reduction in blood pyruvate content
• Reduction in blood lactate content
• Improvement in glucose tolerance
• Reduction in cholesterol count, transaminases, and creatine level

エッチHemodynamic Changes

• Elevation of poststenotic arterial pressure
• Increase in volume of circulation

エッチImprovement in Immune Defenses

• Increase in phagocytosis capability
• Increase in bacteriocidal capacity of blood
• Modulation of the immune status

Infection produces inflammation, edema, and a significant lowering of oxygen tension and diffusion in the affected tissues, which is critical to immune cell functions. Benefits of higher oxygen tension can be seen in the accepted use of hyperbaric oxygen therapy for osteomyelitis, where healthy circulation is already slow. Deductive reasoning would suggest that any rise in oxygen tension would help the body's immune defenses. Such can be seen in anecdotal reports of hyperbaric oxygen therapy alone resolving narcotizing fascitis.

German research (Table 5) documents a rise in oxygen consumption and oxidation within the body stimulation of mitochondrial oxidation results in greater ATP production.

In effect, UV blood irradiation therapy may be providing an inactivation of bacteria, a more resistant terrain, improved circulation, alkalinization, etc. While perhaps not as dramatic a treatment as hyperbaric oxygen therapy, it may provide a similar and longer-lasting effect through the secondary emanations of the absorbed ultraviolet rays. Such emissions, which last for many weeks, may account for the observed cumulative effectiveness of the therapy. UV photons, absorbed by hemoglobin, are gradually released over time, continuing the stimulation to the body's physiology.

For eons, nature has utilized the sun’s ultraviolet energy as a cleansing agent for the earth. The lack of resistance of bacteria to ultraviolet treatment is not surprising since if bacteria could develop resistance, they have had approximately 3 billion years to do so.

Only two discrepancies in accounts of this therapy could be found between the older American and modem German literature. Venous oxygen tension was reported by Miley to be increased, even up to one month after treatment. Frick, on the other hand, reported a rise in PaO2, and a fall in PvO2, suggesting greater oxygen delivery and absorption in the tissues. A rise in 2,3 DGP can account for the latter. Miley recommended the treatment for fevers of unknown original yet Seng's article suggested that as a contraindication. Perhaps the German author feels the infections should be clearly diagnosed first, while Miley was so impressed with his results and the safety of the treatment, he thought it was proper to treat any presumed infection with the technique.

For years, there have been anecdotes and reports of another oxidative therapy (ozone) helping a variety of chronic conditions including, but not limited to, rheumatoid diseases, arterial and circulatory disorders, osteoporosis pain, viruses, and immune deficiencies. Some recent findings shed light on how this particular oxidative therapy might help such a wide variety of conditions.

Bocci has determined that exposure of blood to ozone at concentrations used by practitioners for years induces cytokines and interferons.[35,36] In fact, he went on to call ozone "an almost ideal cytokine inducer." He concluded that such immune system modulation could explain the benefits of ozone reported for decades on a very wide variety of conditions.

Mattman has detailed hundreds of reports linking cell wall deficient bacteria to a wide span of disease states.[37] Autoimmune disease may not be autoimmune at all, but rather an immune attack a hidden infection with native tissue being damaged by a prolonged or dysfunctional immune response to these "stealth pathogens."

The broad spectrum of biologic effects of these nonspecific oxidative therapies may explain the broad range of benefits. It is quite possible that all of the oxidative therapies may operate through similar mechanisms postulated by Bocci for ozone (namely the generation of reactive oxygen species, which in turn induce some very exceptional biochemical events).

Ultraviolet has clearly been shown to be a superior anti-infective. It is possible that the secondary emanations previously described could inactivate pathogens deep in tissues. However, of possible greater import is its effect on the other various physiologic factors affecting the terrain. The improvement in oxygen delivery and consumption, rise in circulation, blood elements, stimulation of mitochondrial oxidation and shift towards alkalinity, while all nonspecific in themselves, may help hasten the cellular response m very many disease states.

Personal experience with UV blood irradiation therapy has been limited strictly to an outpatient practice. However, I have observed significant and dramatic effects on pharyngitis, cellulitis, otitis media, wounds, viral infections, and gastroenteritis, and chronic fatigue. In several years of use, I have had only one patient who suffered from apparent chronic fatigue and failed to respond to a series of UV treatments; the patient had a significant psychological factor. Several patients with multiple chemical sensitivities have also experienced significant improvement. Chronic and intractable pain has been reported by an anesthesiologist pain specialist to be surprisingly responsive.[38]

Modern medicine has focused on drugs to suppress symptoms or inhibit certain physiology (NSAID) drugs as prostaglandin inhibitors, hypertensive drugs as enzymatic blockers) to treat disease. As a result, we have seen the frightening rise of resistant organism and the side-effects of chemical pharmacology. Perhaps medicine should consider the concept of nonspecific modalities that encourage the body's healing response and immune system. What could be a safer or more effective agent against infection than the bacteriocidal capabilities of our own phagocytes and a properly functioning immune system?

At least 20 American physicians are currently utilizing photo-oxidation and have advised me of dramatic cures of intractable infections, including osteomyelitis. Communications from these physicians are verifying my findings in the use of this modality with chronic fatigue. A German videotape related that several hundred physicians are currently employing the technique in Germany with hundreds of thousands of treatments having been performed through the years and never any reported incidents of toxicity (other than a mild Herxheimer reaction).

Ultraviolet irradiation of blood has been approved by the FDA for the treatment of cutaneous T-cell lymphoma. Thus, the method is legal within the context of FDA's definition of legality. It is also legal, from the standpoint of long (over 50 years) and continuous use by physicians in the United States as a commercially viable product before the present FDA was even in existence."[39]

The technique is taught at workshops and seminars sponsored by the International Association of Oxidative Medicine The American Board of Oxidative Medicine (a member of the American Board of Specialties of Alternative Medicine) certifies doctors in the various techniques of oxidative medicine, including UBIT.

Conclusion

This simple, inexpensive, and nonspecific technique was clearly shown years ago to be a totally safe and extremely effective method of treating and curing infections; promoting oxygenation; vasodilatation; improving asthma; enhancing body physiology, circulation, and treating a variety of specific diseases. Its use in hospitals and offices could significantly reduce mortality, morbidity, and human suffering. Much more research needs to be done in determining all of the potential uses of ultraviolet blood irradiation therapy and also its correlation with other oxidative therapies.